WASHINGTON - The Drug Enforcement Administration says heroin and prescription pain pills are among the top drug threats in the U.S. 

The agency released its latest drug threat assessment released Wednesday.

DEA's acting administrator, Chuck Rosenberg, says heroin and prescription drug overdoses combined accounted for nearly three-fourths of the more than 46,000 overdoses. 

Methamphetamine is also a top drug threat, the DEA says. Both meth and heroin are believed to be supplied to illegal drug markets in the United States by Mexico's powerful and violent drug cartels.

The good news, Rosenberg says, is that use and availability of cocaine in the U.S. has declined.